Born in 1983 in Mashhad, grew up in the northern Iranian province of Mazandaran, Misagh Joolaee began to play the violin at the age of eight. Within 5 years he accomplished the learning of the persian-classical repertoire Radif. 1996, Misagh won the first prize in violin solo competition at Fajr Music Festival, the most prestigious music festival in Iran, at the age of 13 in the young performers category on violine. Furthermore he studied setar, tar and especially intensively kamancheh with various iranian masters. Then followed by an eductation on piano and violin in European Classical Music.
 His musical career is characterized by a great versatility in working with musicians of different countries. In 2009 he founded the ensemble AAVAAN, with which he performed his own compositions and won the competition Creole - Global Music in 2010 in Germany.  

Misagh was also a lecturer at the World Music Faculty of the University in Hildesheim from 2011 to 2014. 

In the year 2011 he founded the Anatolian-Persian duo with the turkish Baglama master Levent Ă–zdemir. The two virtuosos play mainly their own compositions together. He also founded in 2015 the Flamenco-Persian Ensemble Chachipen together with significant spanish musicians from Andalusia. 

Furthermore, Joolaee founded 2019 the kamancheh-klavier Duo together with the well-known german pianist Schaghajegh Nosrati.

The solo work is also a focus of his musical activities. In 2014, he appeared as a kamancheh soloist in the performance of the 5th Symphony of Awet Terterjan with the State Orchestra of Braunschweig in the town hall of Braunschweig. 2021 he has been as kamancheh soloist on tour in the Netherlands with Cappella Amsterdam with concerts among others in Muziekgebouw Amsterdam. 
Both of his solo kamancheh CDs, Ferne 2020 and Unknown Nearness 2021, received the most respected and prestigious German Record Critics Award "Preis der deutschen Schallplattenkritik".